Abstract
Chronic hepatitis C (CHC) is one of the common chronic viral infections. Current advances in the treatment of chronic hepatitis C have allowed WHO to develop a Global health sector strategy on viral hepatitis for 2016-2021 with the purpose of its elimination by 2030. Antiviral drugs of new generations have therapeutic efficacy of more than 98% and wide indications for use. At the same time, there are special groups of patients in whom the choice of antiviral therapy regimen is limited and its effectiveness differs from the general population of patients with chronic hepatitis C. This review provides data on the epidemiology, pathogenesis, clinical manifestations of CHC, and current approaches to the treatment of the disease. Particular attention is paid to patients with extrahepatic manifestations of chronic HCV infection.
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