Abstract

A 3-year-old boy with fever, fatigue, and vomiting was admitted to the hospital after failing to respond to antibiotics. His history included frequent throat infections. His physical examination and laboratory findings revealed high body temperature, hyperemic oropharynx with multiple crypts on the tonsils, and elevated acute phase reactants. During follow-up, his temperature normalized but his vomiting increased. With a suspected diagnosis of meningitis, magnetic resonance imaging (MRI) was performed. The MRI findings suggested multiple abscesses (Figs 1 and 2 )a nd meningitis (Fig 1). At surgery the lesions were consistent with abscesses, but no organisms were identified. Additional studies revealed a positive nitroblue tetrazolium test, leading to diagnosis of chronic granulomatous disease (CGD).

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