Abstract

According to Greek mythology, Prometheus is a Titan who stole fire from Zeus and gave it to humans. As punishment, Zeus ordered Prometheus to be chained on top of a mountain, where an eagle came every day to eat his liver. Each day, his liver grew back, only to be eaten again by the eagle. The Greeks recognized Prometheus as an intelligent and cunning character who acted courageously for the benefit of humanity. As physicians and scientists engaged in hematopoietic cell transplantation (HCT), we are the intellectual heirs of our Promethean predecessors who established this life-saving treatment through great creativity, courage, and originality, but we are also heirs of the punishment that follows in the form of our struggles with the chronic graft-versus-host disease (cGVHD) that afflicts many of our patients.

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