Abstract

Chronic fatigue syndrome (CFS) is a common and disabling problem; although most likely of biopsychosocial origin. The nature of the pathophysiological components remains unclear. It is an illness characterized by persistent and relapsing fatigue, often accompanied by numerous symptoms involving various body systems. The etiology of CFS remains unclear. Celiac disease can present with neurological symptoms in the absence of gastrointestinal symptoms; therefore, celiac disease should be included in the differential diagnosis of CFS.Bangladesh Journal of Medical Science Vol.15(3) 2016 p.326-328

Highlights

  • Chronic fatigue syndrome is a complicated disorder characterized by extreme fatigue that can’t be explained by any underlying medical condition

  • Chronic fatigue syndrome (CFS) may be referred to as myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS), chronic fatigue immune dysfunction syndrome (CFIDS)

  • Biometrical genetic modeling suggested that additive genetic factors and common environmental effects each accounted for more than 40% of the variance in liability for chronic fatigue syndrome–like illness, familial predisposition for chronic fatigue of varying intensities, with both genetic and environmental contributions

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Summary

Introduction

Chronic fatigue syndrome is a complicated disorder characterized by extreme fatigue that can’t be explained by any underlying medical condition. Diagnostic criteria To meet the diagnostic criteria of chronic fatigue syndrome, person must have unexplained, persistent fatigue for six months or more, along with at least four of the following signs and symptoms: (a) Loss of memory or concentration (b) Sore throat (c) Enlarged lymph nodes in neck or armpits (d) Unexplained muscle pain (e) Pain that moves from one joint to another without swelling or redness (f) Headache of a new type, pattern or severity (g) Unrefreshing sleep (h) Extreme exhaustion lasting more than 24 hours after physical or mental exercise Investigations include; A full history (including exacerbating and alleviating factors, sleep disturbance and intercurrent stressors) should be taken, and a physical examination and assessment of psychological well being should be carried out. The assessment and treatment of chronic fatigue syndrome should be multidimensional and according to the needs of the individual patient Conflict of interest: None

Chronic fatigue syndrome
Findings
21. Demitrack MA
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