CHRONIC COUGH IS ASSOCIATED WITH DEPRESSIVE MOOD IN GENERAL POPULATION AND COPD PATIENTS: ANALYSIS OF DATA FROM KOREAN NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY FROM 2014 AND 2016

Abstract

SESSION TITLE: Wednesday Abstract Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: 10/23/2019 09:45 AM - 10:45 AM PURPOSE: Chronic cough is one of the most common respiratory symptom. If cough persists for a long time, the quality of life deteriorates and results in depressive mood in these patients. Conversely, depressive mood can trigger the onset of chronic cough. Thus, we aimed to investigate the relationship between depressive mood and chronic cough in general population. METHODS: This was a population-based cross-sectional study. Data were obtained from the 6th Korean National Health and Nutrition Examination Survey, which was conducted from 2014 and 2016. To reduce the effect of CC-related factors and potential confounding factors, propensity score matching was used to match subjects with and without CC. A patient questionnaire was used to check for cough persisting for more than 3 months and the degree of depressive mood was assessed by using the Patient Health Questionnaire-9 (PHQ-9). RESULTS: Among a total of 12,494 subjects, 305 subjects with CC were matched with the same number of non-CC subjects. CC subjects showed a higher PHQ-9 score than non-CC subjects (4.57±5.6 and 2.47±3.5, respectively; p 40, FEV1/FVC≤70%), CC subjects also showed a higher PHQ-9 score than non-CC subjects (4.11±4.92 vs 1.26±2.42, respectively; p=0.001). In multiple logistic regression analysis, CC was associated with the PHQ-9 score in females (odds ratio [OR]=1.17; 95% confidence interval [CI]=1.08-1.27), not male, and in COPD subjects (COPD: OR=1.32, 95% CI=1.09-1.59, p=0.005). CONCLUSIONS: This study demonstrated the relationship between chronic cough and depressive mood. The causal relationship will be clarified. CLINICAL IMPLICATIONS: This study suggest that depressive mood may cause chronic cough. DISCLOSURES: No relevant relationships by Ho Cheol Kim, source=Web Response No relevant relationships by Ju-Young Kim, source=Web Response No relevant relationships by Tae Hoon Kim, source=Web Response