Chronic Consumption of Alcohol-induced Multiple Organ Dysfunction Syndromes with the Involvement of Five Organ Damages: A Fatal Case Report

Abstract

: Multiple organ dysfunction syndromes are defined as damage to one or more organs and failure of homeostasis between anti-inflammatory and pro-inflammatory reactions. This leads the precipitation and activation of inflammatory cytokines and damages tissues results in MODs. The risk factors includes acute severe pancreatitis, sepsis, shock, stroke and alcohol consumption. These multivariable risk factors may precipitate MOD. We presented 25 years of male patients presented with MOD with a history of excess alcohol consumption and associated acute severe pancreatitis, sepsis and renal failure. The laboratory parameters reveal elevated WBC, neutrophil, bilirubin, AST, ALT, serum amylase and lipase, renal function tests and a significant reduction in lymphocytes and platelets counts. Patients died after the 16th day of treatment due to multiple organ failures. Our study concluded that chronic excessive alcohol consumption may lead to MODS and even rarely death.Key words: Multiple Organ Dysfunction Syndromes (MODS), Multiple Organ Failure, Acute Severe Pancreatitis, Excess Alcohol Consumption, Fetal Case Report.