Chronic calculus cholecystitis: A prospective clinico-pathological study with lab based evidence

Abstract

Chronic calculous cholecystitis is an inflammatory disease which affects the gallbladder wall and causes dysfunction of the biliary system. It is the most common benign disease of the gall bladder. To study the pattern of age and sex distribution, diet and clinical feature of patients, the laboratory and radiological investigations of patients presenting with the associated pathology, the intraoperative pathological changes of the gall bladder. This study was conducted from July 2021 to June 2022 at Department of General Surgery, Santosh Medical College and Hospital, Ghaziabad. 100 patients were included in this study. The age, gender, symptomatology, laboratory and radiological findings, intraoperative findings, and histopathological changes where analysed and documented. In our study maximum patients were found in 31-40 years of age. It was found to be most common in females, who consumed mixed diet. The most common symptom was abdominal pain. In ultrasound whole abdomen gall bladder wall thickness was found in majority of the patients. 98% of the patient underwent laparoscopic cholecystectomy and intraoperatively gall bladder was found contracted in 51% of patients. On histopathological examination mild degree of inflammation was seen in 60%, gall bladder wall thickness seen in 50% and the most common type of gall stone was found to be mixed type in 58% patients. We observed the intraoperative pathological changes of the gall bladder, radiological investigations of patients, laboratory investigations of patients and the pattern of age and sex distribution, diet, and clinical feature of patients.