Abstract
A 7-year-old female Doberman pinscher with a history of progressive clinical signs including loss of appetite, diarrhea, vomiting, weight loss, and lethargy was operated through cranial midline incision. There was no abnormality in the abdominal cavity, except for the liver that had yellow appearance and the apex of pancreas which was dark red in color, distorted, and shrunken. Partial pancreatectomy was performed and tissue sample was obtained. Histopathological examination revealed atrophy of exocrine acini and infiltration of mononuclear inflammatory cells including lymphocytes and plasma cells. Loss of glandular tissue of pancreas without replacement, remarkable fibrosis, hemorrhage, and edema in the interlobular tissue associated with numerous hemosiderophages were diagnosed. Microscopically, the lesions were identified as chronic-active pancreatitis.
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