Abstract
A patient with chronic actinic dermatitis showed a leukocytosis with peripheral atypical lymphocytes. Histology of cutaneous eruptions disclosed a dense infiltrate of lymphocytes mixed with large hyperchromatic cells in the dermis and Pautrier-like microabscesses in the epidermis. However, clonal rearrangements of the T-cell receptors were not detected. On the other hand, monoclonal integration of human T-cell lymphotrophic virus type I provirus was found in the peripheral lymphocytes. In the present case, pseudolymphomatous changes occurred in association with adult T-cell leukemia. Southern blot analyses were useful for the correct diagnosis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Photodermatology, Photoimmunology & Photomedicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.