Abstract
The chromosomes were studied in 20 cases of malignant lymphoma, including 9 cases of Hodgkin's disease (HD), 6 lymphosarcomas (LS), 2 reticulosarcomas (RS), 1 follicular lymphoma, 1 atypical lymphoma and 1 chronic lymphocytic leukemia (CLL). Seven of the 20 lymphomas were analyzed with a modified Q-banding technique, 1 of them also with orcein staining, as were the other 13 lymphomas. Exclusively normal karyotype was found in 4 HD, 2 LS. 1 RS and the CLL. The atypical lymphoma was hypodiploid, all the others were in the diploid range with variation towards hyperdiploidy, in 1 HD even towards hypotriploidy. Numeric variation among normal chromosomes involved especially C and E group chromosomes. Marker chromosomes were observed in 8 cases. The isochromosome markers found in 6 cases strongly indicated nonrandomness in the karyotypic variation. The Q-band patterns of some markers were represented diagrammatically by the densitometric computer method worked out by the authors.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
