Abstract

SummaryThe probability of finding a given chromosome in a dicentric is directly proportional to the length of that chromosome at interphase, but not to the length of the early replicating portion of the interphase chromosome or to its length at metaphase. The number of dicentric chromosomes and centric rings per cell is limited primarily by the number of centromeres. These results are consistent with the assumption that every chromosome break is a site for chromosome-exchange.

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