Abstract
DNA analyses of mouse × Chinese hamster somatic cell hybrids and of recombinant inbred mouse strains have previously shown that the interleukin-1 α and β genes are tightly linked on murine chromosome 2, approximately 4.7 cM distal to β-2-microglobulin. In this study, using in situ chromosome hybridization, we show that the two interleukin-1 genes are located in the F region of murine chromsome 2 and discuss this physical map position in relation to conserved genetic linkage groups.
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