Abstract
1. A simple method of cultivation and chromosomal investigation of shortterm cultures of cells from embyronal liver is described which allows a successful chromosomal investigation already from the 2nd-3rd month of intrauterine life.2. From the analysis of the time course of the mitotic activity it resulted that its maximum is before the 72nd hour of cultivation. Afterwards the activity decreases significantly and after the 90th hour of cultivation it disappears completely.3. The chromosomal investigation did not prove a greater amount of chromosomal aberrations, though in the majority of cultures, polyploid cells were in 1-3% of mitoses; endoreduplication was found in one case only.
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