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Abstract
The modal chromosome number of the GF cell line is 46, consisting of 44 telocentrics and two metacentrics. Primary grunt fin tissue exhibits 2n = 48; all are telocentric chromosomes. The modal cell of the GF cell line does not represent the in vivo genetic constitution conserved by Robertsonian translocation since the modal cells are variously haploid or nullo for the chromosome pair bearing secondary constrictions. Despite the fact that GF cells possess 44 telocentric chromosomes, only limited centric fusion appears to have occurred during 8 years of culture in vitro.
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