Abstract
Cytogenetic analysis of human tumors is one of the most rapidly progressing and exciting areas of cancer research. Major advances in our understanding of the specificity of some of the abnormalities observed have occurred within the last 10 years with the application of both chromosome banding techniques and improved methods of cell culture. Thus, the hypothesis put forward by Boveri at the turn of the century, that an abnormal chromosome pattern was intimately associated with the malignant phenotype of the tumor cell, can now be tested with the substantial hope of obtaining a valid answer (Boveri, 1914).
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