Abstract
Chromogranins are acidic proteins confined to secretory granules in neuroendocrine cells (Huttner et al 1991). They seem to have an important role in granule formation (Parmer et al 1993) and to be precursors for biological active peptides (Tatemoto et al 1986). Since chromogranins are localized to neuroendocrine cells (Schmid et al 1989), they may be used as markers for hyperplasia and neoplasia originating from these cells. Moreover, chromogranins are released together with different active hormones/mediators and may be detected in blood by sensitive immunoassay methods (O'Connor et al 1989, Syversen et al 1994).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
