Abstract
Objective: To evaluate the Cica-β test for rapid detection of extendedspectrum β-lactamases (ESBLs) in Gram-negative bacteria. Methods: Forty strains of Pseudomonas spp, Klebsiella spp, Escherichia coli and Enterobacter spp that produce previously characterized β -lactamases were retested using the Cica-β test. This test measures hydrolysis of the chromogenic oxyimino-cephalosporin HMRZ-86 with and without specific inhibitors of extended-spectrum and AmpC s-lactamases. The results were scored according to color changes from yellow to red. Results: A total of 33.3% of extended-spectrum producers and 66.7% of AmpC β-lactamase producers were correctly identified by the Cica-β test. Conclusion: The Cica-β test is not likely to be useful in routine screening for extended-spectrum β-lactamase because it is very expensive and performs poorly in this context.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
