Abstract
Chromoblastomycosis (CM), a chronic subcutaneous mycosis, is caused by several dematiaceous fungi, the most common being Fonsecaea pedrosoi . It usually occurs in the lower extremities following traumatic implantation of the organisms. We are reporting a case of rapidly developing case of CM on the unilateral lower limb with a fungating mass like ulcerative lesion and hyperkeratotic warty growth. We could not explain the pattern of this rapid growth which seems to be one of the rare presentations. Scraping from a verrucous lesion in potassium hydroxide preparation revealed mycelia arising from sclerotic bodies The histopathology from the warty lesion showed granulomatous lesion without muriform or medlar bodies. The histopathology from the ulcerative lesion did not show any malignant changes. Our case responded very well to itraconazole. This case is presented here for the rapidity of growth and the development of a fungating mass and bleeding that simulated the behaviour of squamous cell carcinoma.DOI: http://dx.doi.org/10.3126/njdvl.v8i1.5714 Nepal Journal of Dermatology, Venereology & Leprology 8(1) 2009 22-26
Highlights
Chromoblastomycosis (CM) is a chronic granulomatous mycotic infection of the skin and subcutaneous tissue caused by pigmented fungi, the most common being F pedrosoi
It typically occurs on the exposed surfaces of the lower leg following traumatic implantation of the organisms
Based on the clinical features and positive KOH preparation we diagnosed this as a case of Chromoblastomycosis and started Itraconazole 100 mg twice daily along with daily normal saline dressing after irrigation with hydrogen peroxide solution
Summary
Chromoblastomycosis (CM) is a chronic granulomatous mycotic infection of the skin and subcutaneous tissue caused by pigmented fungi, the most common being F pedrosoi. It typically occurs on the exposed surfaces of the lower leg following traumatic implantation of the organisms. The lesions can involve other sites either by direct spread, autoinoculationor, or, by hematogenous spread. Treatment of CM is frequently difficult and unsatisfactory. We are reporting a case of CM with rapid evolution that responded very well to the treatment with itraconazole. Like fungating mass with oozing of sero- sanguinous and purulent foul smelling discharge with rolled out border on the lateral malleolar region with maggots wriggling within the lesion ( Figures I & 2).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
