Abstract
CrO3 has been found to be an efficient catalyst for benzylic oxidation with periodic acid as the terminal oxidant in acetonitrile. Substituted toluenes with an electron-withdrawing group at the 4- or 3-position and diarylmethanes such as diphenylmethane and fluorene were oxidized to the corresponding substituted benzoic acids and ketones in excellent yields. Benzyl ethers such as isochroman and phthalan were converted to 3,4-dihydroisocoumarin and phthalide in quantitative yields.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
