Abstract
Chromatography on a modified cellulose anion-exchange paper has been used to separate mixtures of certain 5,5-substituted barbiturates. Aqueous “solvents” were found to be unsatisfactory but organic solvents gave good resolution in a shorter time than with “ordinary” filter paper. Complete resolution of a mixture of Phenobarbitone, Barbitone, Butobarbitone and Quinalbarbitone can be achieved in 4 hours.
Published Version
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