Abstract
Abstract : Extracts of tentacles from the jellyfish Chironex fleckeri which possessed strong hemolytic properties were examined by ion exchange chromatography on carboxymethyl and diethylaminoethyl cellulose and by exclusion chromatography on Sephadex G-75 and G-200. In some experiments the hemolytic activity was related quantitatively to the lethality of the samples to mice, before and after the separatory procedure used. It was concluded that the hemolytic activity of the extracts was due to a single component, a protein of molecular weight of approximately 70,000. At least one other toxic component was present, which had a molecular weight of approximately 150,000. Methods for purifying the hemolysin are suggested. (Author)
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Schedule a callMore From: Toxicon : official journal of the International Society on Toxinology
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