Abstract
The regularities of the biodegradation of drotaverine hydrochloride in soil by actinobacteria of the genus Rhodococcus in the presence of native microflora were studied. A method based on liquid–liquid extraction with chloroform followed by analysis using reverse-phase HPLC was proposed for determining the pharmaceutical pollutant in soil. A decrease in the ecotoxicant concentration by a factor of 100 in the course of its biodegradation was forecasted with a given probability of 95%.
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