Abstract
A partition chromatographic method is presented for the separation and quantitation of chlorpheniramine, methapyrilene, and pyrilamine in combination.A solution of p-toluenesulfonic acid and potassium chloride on a column of diatomaceous earth is used to effect the separation.The isolated chlorpheniramine is determined by UV spectrophotometry.The methapyrilene and pyrilamine are separated and determined by GLC.
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