Abstract
BOTH adrenaline and its possible precursor nor-adrenaline can be obtained from the adrenals of many animals in the different classes of vertebrates1. In the dogfish, where adrenocortical and chromaffin tissue are entirely separate, the latter contains wholly noradrenaline2. In the Amphibia, where the two tissues are intermingled, noradrenaline forms 50–69 per cent of the total catechol content in the frog2 and 35–58 per cent in the toad3. In the eutherian mammal, chromaffin tissue, formed as a medulla surrounded by cortical tissue, produces mostly adrenaline1,2,4.
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