Abstract
The Collaborative Ocular Melanoma Study (COMS) group has identified 4 American Indian patients among the first 5987 patients with choroidal melanomas who were evaluated in COMS centers. To our knowledge, uveal melanomas have not been previously described in American Indians. 1 Two full-blooded American Indian patients had darkly pigmented, large choroidal melanomas that required enucleation. Two patients with mixed ancestry received radiotherapy for medium-sized choroidal melanomas. Report of Cases. Case 1. A 76-year-old, full-blooded American Indian man was examined to determine whether he had a choroidal melanoma. Ten months earlier, his visual acuity had abruptly decreased to 20/100 OD because of a submacular hemorrhagic mass. Enlargement of the mass, accompanied by extensive, pigmented vitreous cells, was noted 2 months earlier; a vitreous hemorrhage was diagnosed. Bronze skin and dark black hair were noted on external examination. No abnormal skin or episcleral pigment was noted. A 13.8-mm-thick, collar-button shaped, heavily pigmented
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