Abstract
Among the tumors affecting the choroid plexus in dogs, the papilloma ranks second place in incidence after cell carcinoma tumors. Presumptive diagnosis can be made through imaging methods, such as computed tomography and magnetic resonance images. Definitive diagnosis of plexus choroid tumor is based on histopathological findings. This report presented the tomographic features of the brain in a 6-year-old intact female Rottweiler with choroid plexus papilloma. The computed tomography showed right lateral ventricle enlargement, midline deviation and an enhanced mass into the postcontrast phase. At necropsy, a mass on the floor of the right lateral ventricle was observed, associated with important ventricle dilatation. The histopathological analysis demonstrated the presence of neoplastic cell forms with papillary projections. The computed tomography proved to be an effective tool in the presumptive diagnosis of this kind of cerebral disorder.
Highlights
The choroid plexus epithelium originates from the differentiation of the primitive medullary epithelium and it is embryologically related to ependymal cells (Hammer et al, 1990)
In an earlier study of dogs with choroid plexus tumors (CPT), Choroid plexus carcinoma (CPC) and choroid plexus papilloma (CPP), conducted by Westworth et al (2008), the cerebrospinal fluid (CSF) analysis of dogs affected by CPC evidenced an increased protein concentration, with a median of 108mg/dL significantly higher than the values of the animals with CCP, which had a median of 34mg/dL
CPT do affect the fourth ventricle, they may appear in other areas of the ventricular system
Summary
The choroid plexus epithelium originates from the differentiation of the primitive medullary epithelium and it is embryologically related to ependymal cells (Hammer et al, 1990). The floor of each lateral ventricle and the roof of the third and fourth ventricles of the brain are partly covered by an epithelium called “tela choroidea”, in which blood microvessels originate, covering the ependymal epithelium This vascular structure is projected into the ventricular cavities in the form of villi, giving rise to the choroid plexus (CP). In an earlier study of dogs with choroid plexus tumors (CPT), CPC and CPP, conducted by Westworth et al (2008), the CSF analysis of dogs affected by CPC evidenced an increased protein concentration, with a median of 108mg/dL (reference range:
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