Choriocapillaris Changes Imaged by OCT Angiography After Half-Dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy.

Abstract

To evaluate the choriocapillaris using optical coherence tomographic angiography (OCTA) after half-dose verteporfin photodynamic therapy (hd-PDT) for chronic central serous chorioretinopathy (CSC). We studied six eyes (six patients) with chronic CSC treated by hd-PDT. OCTA was performed before, 1 week after, and 1 month after hd-PDT. The area of flow abnormality at the choriocapillaris level within the PDT spot after hd-PDT was compared with that before hd-PDT. Serous retinal detachment was diminished in all eyes, with three achieving complete resolution at 1 month. On OCTA, all eyes showed irregular choriocapillaris flow before hd-PDT. The areas of abnormal flow shrank progressively at 1 month after hd-PDT. On OCTA, choriocapillaris flow tended to recover at 1 month after hd-PDT. OCTA may be clinically useful for evaluating choriocapillaris and the therapeutic effects of hd-PDT for chronic CSC. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:302-310.].