Abstract
In 1923, Dr. E. C. Rosenow 1 of Rochester, Minn., reported that he had isolated streptococci which grew on blood agar in small, dry, slightly elevated and nonadherent colonies, surrounded by a brownishgreen zone, from the nasopharynx and the tonsils of patients having chorea. After twenty-four hours a narrow zone of hemolysis developed, peripheral to the green zone. By injecting these bacteria into the cranial cavity and into the roots of teeth of various animals, he was able to produce in rabbits a disease much resembling chorea. In addition, examination of the valves of the heart revealed a definite tendency of these organisms to localize there. He prepared a monovalent serum that had the property of agglutinating specifically the organisms he had isolated. He was kind enough to permit us to study the effect of this serum on our patients in the hospital who had chorea. In planning the work,
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