Abstract
Background A COS represents an agreed minimum set of outcomes that should be measured and reported in all trials of a specific condition. The COMET (Core Outcome Measures in Effectiveness Trials) initiative aims to collate and stimulate the development and application of COS, by including data on relevant studies within a publically available internet-based resource. In recent years, there has been an interest in increasing the development of COS. Therefore, this study aimed to provide an update of a previous review, and examine the quality of development of COS. A further aim was to understand the reasons why individuals are searching the COMET database.
Highlights
A COS represents an agreed minimum set of outcomes that should be measured and reported in all trials of a specific condition
A multi-faceted search strategy was followed, in order to identify studies that sought to determine which outcomes/ domains to measure in clinical trials of a specific condition
A pop up survey was added to the Core Outcome Measures in Effectiveness Trials (COMET) website, to ascertain why people were searching the COMET database
Summary
A COS represents an agreed minimum set of outcomes that should be measured and reported in all trials of a specific condition. The COMET (Core Outcome Measures in Effectiveness Trials) initiative aims to collate and stimulate the development and application of COS, by including data on relevant studies within a publically available internet-based resource. There has been an interest in increasing the development of COS. This study aimed to provide an update of a previous review, and examine the quality of development of COS. A further aim was to understand the reasons why individuals are searching the COMET database
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