Chondrosarcoma of the hyoid treated with interstitial photodynamic therapy: Case study

Abstract

Chondrosarcoma;Hyoid;PhotodynamictherapyChondrosarcoma is a malignancy that is cartilaginous in ori-gin and represents approximately 25% of all primary osseousneoplasms. Chondrosarcomas are rare with 90 new cases ayearreportedintheUK.Ofthese,only10%occurintheheadandneck.Peakincidenceisbetweentheagesof30—50,withno apparent correlation with gender [1,2].There are two common grading systems for chondrosar-comas. They can be graded 1—3, with 1 being the leastaggressive and 3 the most. Alternatively, chondrosarcomasare graded low or high grade, with low grade tumours char-acterised by well-differentiated cells and high grade poorlydifferentiated, with a high mitotic rate [1,2].Approximately 90% of conventional chondrosarcomas arelow to intermediate grade that have low metastatic poten-tial, and the rest are high grade or grade 3 lesions with ahigh metastatic rate. The 5-year survival rate of patientswith grade 1, 2, and 3 tumors were 90%, 81%, and 43%,