Abstract
Chondrosarcoma (CS) is a malignant neoplasm of mesenchymal origin characterized by the formation of cartilaginous matrix by neoplastic cells. It is very variable in presentation, clinical, genetic and anatomo-pathological features. CS is more often found in the pelvis and the proximal long bones (femur, humerus). Localization to the small bones of the hand is very rare and it represents a diagnostic and therapeutic challenge. CSs are malignancies resistant to both radiation and chemotherapy . Surgical treatment is the only mean available. As opposed to CSs located elsewhere, CS of the hand is characterized by local recurrence and very low metastatic potential. In order to definitely set a diagnosis of chondrosarcoma in this region, comparison of histological and radiological findings is paramount. The principle goal of surgery shall be minimizing functional impairment. This provides the rationale for performing curettage, local adjuvant therapy and bone grafting in low-grade lesions.
Highlights
Chondrosarcoma (CS in the text) is a malignant tumour of mesenchymal origin characterized by the formation of cartilaginous matrix by neoplastic cells
It is very difficult to distinguish enchondroma from chondrosarcoma, since the former shows several of these features, especially when located in the hands
We found reports including CSs arising in patients with Ollier’s disease [3] and Maffucci’s Syndrome [19] affecting the hands: the former being multiple enchondromatosis generally with unilateral predominance, the lattermultiple enchondromatosis associated with multiple haemangiomas
Summary
Chondrosarcoma (CS in the text) is a malignant tumour of mesenchymal origin characterized by the formation of cartilaginous matrix by neoplastic cells. It is very variable in presentation, clinical, genetic and anatomopathological features. It can be both primary and secondary. CS usually presents in the conventional or typical form, i.e., primary and central. How to cite this paper: Stomeo, D., et al (2014) Chondrosarcoma of the Hand: A Literature Review.
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