Abstract
Chondromyxoid fibroma (CMF) is one of the rarest benign tumors of cartilaginous origin. It accounts for less than 0.5% of bone tumors and less than two percent of benign bone tumors. It is composed of a mixture of chondroid, myxoid, and fibrous tissues. The diagnosis of CMF depends upon its characteristic histological appearance like a lobular pattern with stellate-shaped cells in a myxoid or chondroid background. We present a case of juxtacortical CMF in a 15-year-old male involving the proximal end of the tibia, which was treated with en bloc excision and bone grafting with excellent results on final follow-up.
Highlights
Chondromyxoid fibroma (CMF) is one of the rarest benign tumors of cartilaginous origin. It accounts for less than 0.5% of bone tumors and less than two percent of benign bone tumors [12]
It mainly affects the metaphysis of long bones, the proximal tibia being the most common location
It mostly occurs in patients who are 10 to 30 years old and presents more commonly in men than in women [1, 3]. It is composed of a mixture of chondroid, myxoid, and fibrous tissues [1]
Summary
Chondromyxoid fibroma (CMF) is one of the rarest benign tumors of cartilaginous origin. It mainly affects the metaphysis of long bones, the proximal tibia being the most common location It mostly occurs in patients who are 10 to 30 years old and presents more commonly in men than in women [1, 3]. A 15-year-old male patient presented with a four-month history of pain at the proximal end of the right tibia. A radiographic examination showed an osteolytic, radiolucent, eccentric lesion in the metaphysis at the medial border of the proximal tibia, with sclerotic margin and septations with no evidence of periosteal new bone formation [Figure 1]. A histopathological examination of multiple serial sections showed bony tissue with fibrocollagenous stroma and myxochondroid islands with stellate-shaped cells, which confirmed the diagnosis of CMF [Figure 5]. The images show good incorporation of the graft and no signs of recurrence
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