CHONDROID SYRINGOMA WITH EXTENSIVE MATURE BONE AND CARTILAGE FORMATION: A CASE REPORT AND REVIEW OF THE LITERATURE

Abstract

<h3>Background and Objective</h3> Chondroid syringoma is a rare skin adnexal tumor, mostly involving the head and neck region. It is usually present as a skin painless nodule. We present a rare case of chondroid syringoma with extensive mature bone and cartilage formation. <h3>Methods</h3> Chondroid syringoma usually presents as a skin painless nodule. The histopathology is usually composed of a variable mixture of epithelial and myoepithelial structures on a background of chondromyxoid and fibrous stroma. It rarely shows mature bone or cartilage formation. <h3>Results</h3> To the best of our knowledge, only several cases of chondroid syringoma with bone formation and few cases of chondroid syringoma with cartilage formation have been reported in published studies to date. We report a case of chondroid syringoma with extensive mature bone and cartilage formation that is probably the first reported case showing this mixture of appearances. <h3>Conclusions</h3> Histopathologically, the presence of tumor with extensive mature bone and cartilage formation may cause diagnostic difficulties and wide differential diagnosis. Therefore, awareness of this rare entity can be helpful to avoid future diagnostic pitfalls, particularly when the appearances are unusual.