Abstract
Purpose: Adult hyaline articular cartilage is an avascular tissue that does not fully regenerate on itself. Gene transfer using the clinically relevant recombinant adeno-associated viral (rAAV) vectors is a powerful tool to enhance cartilage repair [1]. Here, we tested the ability of poly(sodium styrene sulfonate) (pNaSS)-grafted microstructured poly(ε-caprolactone) scaffolds to deliver chondrogenic rAAV sox9 and TFG-β vectors to human bone marrow aspirates, a potential source of reparative cells for cartilage repair.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
