Abstract
In general, aging appears to reduce an organism's ability to metabolize lipid (Kritchevsky, 1972). Cholesterol synthesis (Bloch et al., 1946), degradation (Yamamoto and Yamamura, 1971) and turnover (Hruza and Wachtlova, 1969) are all reduced in aging rats. Fatty acid synthesis and oxidation by rat epididymal fat are also reduced (Benjamin et al., 1961). Aortic metabolism does not appear to follow this trend. Zemplenyi and Grafnetter (1959) and Dury (1961) measured lipolysis by aortic tissue and found lipolytic activity higher in old than in young rats. Cholesterol ester synthetase and hydrolase activities are also higher in old than in young rats (Kritchevsky et al., 1973 b). We would like to report the results of preliminary experiments to determine the uptake of cholesterol in vitro by aortas from young and old rats.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
