Cholesterol content of the coronary arteries and blood in acute coronary artery thrombosis

Abstract

1. 1. The average cholesterol content of the coronary arteries in a group of patients who died from an acute coronary artery thrombosis was four times as great as the average cholesterol content of the coronary arteries in a comparable group of control patients. 2. 2. Hypercholesterolemia was found in most of the patients who died of acute coronary artery thrombosis, as compared to a normal blood cholesterol average in the comparable control group. 3. 3. These findings suggest that a disturbance in lipid metabolism is a factor in the pathogenesis of atherosclerosis.