Abstract

Unilamellar liposomes were investigated by capillary electrophoresis, light scattering, and monolayer penetration techniques. Zwitterionic liposomes with and without cholesterol were compared and the effects of pH (7.40 and 8.25) and buffer (various sulfonic acid buffers, Tricine, and phosphate) on the electrophoretic mobilities and sizes of the liposomes were studied. Anionic liposomes containing phosphatidylserine with and without various amounts of cholesterol were used as dispersed phase in electrokinetic capillary chromatography in the separation of six steroidal hormones, with a focus on selectivity differences with increasing amounts of cholesterol in the liposomes. The results were confirmed by monolayer penetration measurements.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.