Abstract

Although cholesterol is thought to be uncommon in plant tissues, this sterol is widely used in artificial diets for phytophagous as well as carnivorous insects. Levinson (1962) suggested that a variety of phytophagous insects convert plant sterols to cholesterol. Noland (1954) also showed that certain structural analogs of cholesterol act as cholesterol antimetabolites in the German cockroach, Blattella germanica (L.). He postulated that this antimetabolic activity was due to the competitive inhibition of cholesterol esterase. Cholesteryl chloride is a cholesterol antagonist for the larvae of the oriental house fly, Musca domestica vicina Macquart (Levinson and Bergmann 1957), and reversibly inhibits the utilization of tissue sterols of the yellow meal-worm, Tenebrio molitor L., by Dermestes maculatus DeGeer larvae (Levinson 1962). However, Robbins et al. (1961) found that utilization of cholesterol by German cockroaches decreased only 9–11% when cholesterol and cholesteryl chloride were included in the diet at a 1:10 ratio.

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