Abstract
Telepaque2 a new cholecystographic medium, is an iodine substituted organic compound, containing 66.68 per cent iodine as compared with 51.38 per cent in the cholecystographic medium now widely used. The chemical formula is: 3- (3-amino - 2,4,6 - triiodophenyl)-2-ethylpropanoic acid. Telepaque is supplied in 0.5-gram tablets which are about the size of aspirin tablets and easily swallowed. Experimental studies in animals have demonstrated a wide margin of safety in the doses used to opacify the gallbladder (1). To evaluate the clinical usefulness of the new agent, it was given to a consecutive series of patients who had been referred, because of symptoms, for roentgen study of the gallbladder. The telepaque tablets were issued by the Drug Department of the University of Minnesota Hospitals with no attempt at selection of cases. For the first series (83 cases), six tablets (3.0 grams) were given to each patient. Concurrently, a control series of cases was recorded using the cholecystographic medium now in ...
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