Abstract
Two young patients with cholangiocarcinoma associated with salmonella carriage and ulcerative colitis, respectively, were seen at a community- based university hospital. This experience prompted a review of all cases with this tumour seen in the past decade. Twenty-seven patients were found. Their clinical, laboratory, and histological features, and therapeutic outcome are described. Of the group, only 7.4% were younger than 30 years of age and 14.8% had recognized associated conditions. The most common definable tumour was a well differentiated hilar cholangiocarcinoma. Overall outcome was poor (six months). Survival was similar in patients undergoing palliative stents or surgery. In a small subgroup of surgically treated patients who received either radiotherapy or postoperative drainage, survival seemed to be better.
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