CHnical diagnosis and treatment of 21 patients with hyperlipidemic acute pancreatitis

Abstract

Objective To investigate the clinical diagnostic and therapeutic measures of hyperlipidemic acute pancreatitis(HLAP).Methods A retrospective study on the clinical data of 21 patients with HLAP was conducted in comparison with the data of 42 patients with non-HLAP during the period between Jun,2006 and Jun,2011.And the correlation between TG and RANSON score was analyzed.Results For patients with HLAP:six out of seven patients studied were male,with the average onset age being 46.3 years old.Compared with the non-HLAP group,the HLAP group had more male and younger patients,and the levels of TG,blood glucose,CRP,ALT and AST were evidently higher than those in the non-HLAP group.And there were significant differences between the two groups(P＜0.05).The RANSON score in HLAP group was obviously higher than that in non-HLAP group(P＜0.05).Furthermore,the correlation between TG and RANSON score in all the patients,especially in the HLAP group with acute biliaty pancreatitis(P＜0.01).Conclusions There is an close relationship between hypertriglyceridemia and acute pancreatitis,the high level of plasma TG plays a key role in acute pancreatitis,acute pancreatitis patients with hypertriglyceridemia are more likely to be severe and has poor prognosis.So early blood lipid test,diagnosis and treatment of HLAP should be carried out to prevent relapse of the disease. Key words: Hypertriglyceridemia; Acute pancreatitis; RANSON score; Diagnosis; Treatment