Chloroquine diphosphate therapy in Weber-Christian syndrome.

Abstract

Case Reports1 October 1959CHLOROQUINE DIPHOSPHATE THERAPY IN WEBER-CHRISTIAN SYNDROMEWALTER K. MYERS, M.D., F.A.C.P.WALTER K. MYERS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-4-791 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRelapsing febrile nodular nonsuppurative panniculitis (Weber-Christian syndrome) has been recognized with increased frequency. Little is known concerning its etiology. No specific therapy has been available.Two cases of Weber-Christian syndrome are reported. The responses to chloroquine diphosphate were quite dramatic and gratifying.CASE REPORTSCase 1. A white woman was first seen in May, 1947, when she was 40 years of age. For five years she had had recurrent attacks of painful, tender nodules in the calves of the legs and in the left thigh. Walking and standing gave rise to symptoms varying from discomfort to severe pain. On three...Bibliography1. AldersonWay HESC: Relapsing febrile nonsuppurative panniculitis (Weber), Arch. Dermat. and Syph. 27: 440, 1933. CrossrefGoogle Scholar2. Bailey RJ: Relapsing, febrile, nonsuppurative panniculitis (Weber-Christian disease), J. A. M. A. 109: 1419, 1937. CrossrefGoogle Scholar3. De LoiMartz CJRW: Weber-Christian disease with bone involvement, Ann. Int. Med. 43: 591, 1955. LinkGoogle Scholar4. HansonFowler WALH: Relapsing febrile nodular nonsuppurative panniculitis, Minnesota Med. 24: 779, 1951. Google Scholar5. Andrews GC: Diseases of the skin, 1954, W. B. Saunders Company, Philadelphia, p. 547. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Received for publication May 12, 1958.From the Departments of Medicine, The George Washington University School of Medicine and The Washington Medical Center, Washington, D. C.Requests for reprints should be addressed to Walter K. Myers, M.D., 1834 Eye Street, Northwest, Washington 6, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySuccessful Treatment of Idiopathic Febrile Panniculitis (Weber-Christian Disease) with Thalidomide in a Patient Having Failed Multiple Other Medical TherapiesChloroquine-induced remission of nodular panniculitis present for 15 yearsWeber-Christian disease with facial involvementA case of Weber-Christian disease with roentgenographically demonstrable mammary calcificationsRheumatism and Arthritis Review of American and English Literature of Recent Years (Fourteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., ROGER L. BLACK, M.D., CHARLES L. CHRISTIAN, M.D., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., EDWARD C. FRANKLIN, M.D., DONALD F. HILL, M.D., F.A.C.P., JOSEPH L. HOLLANDER, M.D., F.A.C.P., HOWARD L. HOLLEY, M.D., F.A.C.P., JOHN G. MAYNE, M.D., WILLIAM M. MIKKELSEN, M.D., CHARLES L. SHORT, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P.(C), OTTO STEINBROCKER, M.D., HOWARD J. WEINBERGER, M.D. 1 October 1959Volume 51, Issue 4Page: 791-795KeywordsChloroquineEtiologyLesionsWalking ePublished: 1 December 2008 Issue Published: 1 October 1959 PDF downloadLoading ...