Abstract
Artemisia annua produces lifesaving antimalarial drug artemisinin. The biosynthetic pathway of artemisinin is intercalated with chloroplasts of A. annua. Therefore, it will be imperative to optimize its chloroplast transformation for increasing the yield of artemisinin, which has not been achieved to desired levels via nuclear genome transformation (Ikram and Simonsen, 2017). The low yield has limited its current global demand for the artemisinin based combination therapies (ACTs).
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