Abstract
AbstractThe 13C and 1H nmr spectra of chloroindoles and chlorotryptophans in methanol‐d4 were assigned based on 1‐D and 2‐D nmr techniques, including COSY, inverse‐detected direct (HMQC) and long‐range (HMBC) correlation. Chlorine substitutent effects in chemical shifts (SCS) for chlorotryptophans and chloroindoles were calculated and compared. The correlations were linear except for 4‐chlorotryptophan, which suggests structural changes on the indole ring between 4‐chlorotryptophan and 4 chloroindole. The conformational analysis based on the coupling constants of the side chain also showed a change in the fractional population of the rotamers between 4‐chlorotryptophan and the other chlorotryptophans.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
