Abstract
The effect of post-irradiation chloramphenicol treatment (PCT) on a number of radiation-sensitive mutants of Escherichia coli B and Escherichia coli K12 was investigated. The two unsuppressed lon mutants and all four exrA mutants examined were rescued by PCT. The Lon strains which filamented extensively after irradiation and showed a higher survival when grown in the presence of pantoyl lactone, were probably rescued by PCT as a consequence of suppression of filament formation; the recovery process acting in the exrA mutants in now known. Survival of recA, recB or pol mutants was little affected, whilst both exrA strains mutated at sul suffered further killing.
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