Abstract
Aorta cholesterol ester fatty acid composition has been studied in 27 cases ranging in age from 11 through 37 years. The composition of the major fatty acids esterified to cholesterol in descending thoracic aorta fatty streaks is different from that in normal intima from the same individual. Fatty streaks contained a greater proportion of cholesterol palmitoleate, oleate and eicosatrienoate and a lesser proportion of palmitate and linoleate than normal intima. There appeared to be a trend toward greater differences in cholesterol ester fatty acid composition between fatty streaks and normal intima in the third decade of life than in the second and fourth. No real difference in cholesterol ester fatty acid composition was found between thoracic aorta fatty streaks and abdominal aorta fatty streaks. Analysis of the trienoic acid esterified to cholesterol revealed it to be eicosatrienoic acid, probably the 8,11,14 isomer.
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