Abstract
Chlamydialike Organisms and Atherosclerosis
Highlights
Parachlamydia acanthamoebae and Neochlamydia hartmanellae are chlamydialike organisms that share ≈86% 16S rRNA sequence similarity with C. pneumoniae [5]
We investigated the role of Parachlamydia in pathogenesis of atherosclerosis by using a molecular approach
Despite the small number of patients in this study, this association was confirmed in a multivariate logistic regression model adjusted for sex and previous cardiovascular disease. These findings suggest that Parachlamydia and Neochlamydia are associated with atherosclerosis
Summary
Parachlamydia acanthamoebae and Neochlamydia hartmanellae are chlamydialike organisms that share ≈86% 16S rRNA sequence similarity with C. pneumoniae [5]. Like C. pneumoniae, they have elementary and reticulate bodies visible by electron microscopy [6]. AF097191) has been amplified from 5 different arterial samples, including 1 aortic aneurysm [7], and a relationship (p = 0.009) between cerebral hemorrhage and serologic evidence of Parachlamydia infection has been reported [8]. We analyzed 78 surgical samples from 27 patients undergoing aortic or carotid surgery for atherosclerotic disease at Hôpital Nord in Marseille from June 1, 2003, to December 31, 2003.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
