Abstract
Chlamydia trachomatis infections are the most prevalent sexually transmitted bacterial infections in the world and a woman infected during pregnancy can transmit C. trachomatis to her infant who is then at an increased risk of developing eye and lung complications such as conjunctivitis and pneumonia. To date the only data available referring to the distribution of C. trachomatis serovars in ophthalmia neonatorum worldwide are related to trachoma serovars. The information on the prevalence of C. trachomatis infections and serovars in Argentina is scarce. To identify the serovars of C. trachomatis associated with ophthalmia neonatorum and genital infections circulating in the metropolitan area of Buenos Aires (Argentina) we studied 777 ocular swabs from newborn babies with neonatal conjunctivitis as well as 2376 endocervical swabs and 860 male urethral swabs from symptomatic adults. Specimens were collected from patients who attended two public hospitals demanding diagnosis (the National Hospital Prof. Dr. A. Posadas and the University of Buenos Aires Hospital Hospital de Clinicas Jose de San Martin) between January 2000 and December 2004. Samples were analyzed either by ELISA or by cell culture/ompA PCR respectively. Every positive sample was confirmed and genotyped by PCR-RFLP over C. trachomatis ompA gene as previously described. (excerpt)
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