Abstract
The increasing abiotic stresses from changing global climatic conditions, including drought, extreme temperatures, salinity, storms, pollutants, and floods, impend crop cultivation and sustainability. To mitigate these effects, numerous synthetic and non-synthetic chemicals or plant growth regulators are in practice. Chitosan, a natural organic substance rich in nitrogen and carbon, and thiourea, a synthetic plant growth regulator containing sulfur and nitrogen, have garnered significant interest for their roles in enhancing plant stress tolerance. Despite extensive use, the precise mechanisms of their actions remain unclear. Towards this endeavor, the present review examines how chitosan and thiourea contribute to stress tolerance in crop plants, particularly under drought conditions, to improve production and sustainability. It also explores thiourea's potential as a hydrogen sulfide (H2S) donor and the possible applications of thiolated chitosan derivatives and chitosan-thiourea combinations, emphasizing their biological functions and benefits for sustainable agriculture.
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