Abstract
Chitosan–hydroxyapatite composite layers were deposited on Si substrates in radio frequency magnetron sputtering discharges. The plasma parameters calculated from the current–voltage radio frequency-compensated Langmuir probe characteristics indicate a huge difference between the electron temperature in the plasma and at the sample holder. These findings aid in the understanding of the coagulation pattern of hydroxyapatite–chitosan macromolecules on the substrate surface. An increase in the sizes of the spherical-shape grain-like structures formed on the coating surface with the plasma electron number density was observed. The link between the chemical composition of the chitosan–hydroxyapatite composite film and the species sputtered from the target or produced by excitation/ionization mechanisms in the plasma was determined on the basis of X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy and residual gas mass spectrometry analysis.
Highlights
Coatings based on hydroxyapatite are used in different biomedical applications such as bone substitution and bone regeneration due to the similarities between their chemical composition and the one corresponding to the inorganic component of bone structures [1,2,3]
We showed that at low radio frequency working powers, in magnetron sputtering plasma discharges, bioceramic multicomponent coatings for biomedical applications can be synthetized [10,11,12]
In [10], we showed that in rf magnetron discharge at about 1.2 × 10−2 mbarr and 50 W rf power, after 4 h deposition time, regular granular-like structures on the surface of calcium phosphate layers deposited on Ti substrates can be generated
Summary
Coatings based on hydroxyapatite are used in different biomedical applications such as bone substitution and bone regeneration due to the similarities between their chemical composition and the one corresponding to the inorganic component of bone structures [1,2,3]. Thin films of hydroxyapatite that cover implants and scaffolds for tissue substitution promote cells and proteins adhesion, are used to simulate osteoblast activity and increase the mechanical strength of the substrates. Chitosan ((C6 H11 NO4 )n ) is a polymer with bioactive, bioabsorbable and antimicrobial properties, being nontoxic to the human organism. It is used in biomedical applications for scar-free wound healings or anti-inflammation therapy due to its capacity to slowly release medicines [5]
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